Retatrutide vs Cagrilintide
These compounds work through unrelated receptor families. Retatrutide activates the GIP, GLP-1 and glucagon receptors. Cagrilintide is a long-acting analogue of amylin and activates amylin and calcitonin receptors.
Investigational GIP, GLP-1 and glucagon triple agonist
Choose Retatrutide if
- ✓ Your question involves GIP, GLP-1 or glucagon receptor activity
- ✓ You are comparing single, dual and triple agonists
Long-acting amylin and calcitonin receptor agonist
Choose Cagrilintide if
- ✓ Your question is about amylin or calcitonin receptor signalling
- ✓ You are studying a non-incretin satiety pathway
Side-by-side specification
| Compare | Retatrutide Investigational GIP, GLP-1 and glucagon triple agonist | Cagrilintide Long-acting amylin and calcitonin receptor agonist |
|---|---|---|
| Class | Triple GIP / GLP-1 / glucagon agonist | Amylin / calcitonin receptor agonist |
| Research area | Metabolic | Metabolic |
| Receptor targets | GIPR, GLP-1R, GCGR | Amylin and calcitonin receptors |
| Length | ≈ 40 amino acids (fatty-acid modified) | 37 amino acids (acylated amylin analogue) |
| Molecular mass | ≈ 4.7 kDa | ≈ 4.41 kDa |
| Origin | Synthetic | Synthetic analogue of human amylin |
| Evidence level | 4/5 Late-stage human trials | 4/5 Late-stage human trials |
| Regulatory status | Investigational | Investigational |
| Nordapep from | £63.40 | — |
| Best price per mg | £5.09/mg | — |
| View Retatrutide at Nordapep → | Browse Nordapep → |
What separates them
Both are investigational and both are fatty-acid modified for a long half-life. For research, retatrutide is the tool for multi-receptor incretin questions, and cagrilintide is the tool for amylin biology, which is why it is often studied alongside a GLP-1 agonist rather than instead of one.
Read the full guides for Retatrutide and Cagrilintide, or add a third compound in the comparison tool.
FAQ
Do retatrutide and cagrilintide share a receptor?
No. Retatrutide acts on three receptors of the incretin and glucagon family; cagrilintide acts on amylin and calcitonin receptors.
Is either approved?
No. Both are investigational compounds in clinical development. Research-grade material is for in vitro use only.
Are Retatrutide and Cagrilintide approved medicines?
Retatrutide: Investigational. Cagrilintide: Investigational. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy Retatrutide and Cagrilintide?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
More comparisons
Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.