At a glance
- Class
- Dual GIP / GLP-1 receptor agonist
- Receptor targets
- GIPR, GLP-1R
- Length
- 39 amino acids (acylated)
- Molecular mass
- ≈ 4.81 kDa
- Origin
- Synthetic, GIP-based sequence
- Research area
- Metabolic & incretin research
- Also known as
- –
What Tirzepatide is
Tirzepatide is built on the sequence of GIP with modifications that also give it strong GLP-1 receptor activity, plus a fatty-acid side chain for a long half-life.
Researchers use it to ask what adding GIP-receptor activity changes compared with GLP-1 alone, which is why it is so often paired with semaglutide in comparison studies.
What the research literature studies
- Biased agonism at the GIP and GLP-1 receptors in cell models
- Comparison of dual versus single incretin receptor signalling
- Peptide stability and albumin binding after acylation
Evidence rating: 5/5
Approved drug, phase 3 trials. Approved medicine backed by large randomised phase 3 programmes. See our methodology for how levels are assigned.
- Mechanistic explanations for how GIP activity contributes are still debated in the literature.
- Human outcome data belong to the branded medicine and are not evidence for research material.
Regulatory status
Tirzepatide is authorised as a prescription medicine in the UK, EU and US under brand names. Research-grade material is not that medicine and must not be used in people or animals.
Reviewed November 2026.
Tirzepatide at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare Tirzepatide
Tirzepatide FAQ
Is tirzepatide more potent than semaglutide?
Potency depends on the assay and receptor. They are different molecules with different receptor profiles, so direct comparisons only make sense within one experimental system.
Where can I buy Tirzepatide for research?
Nordapep does not currently list Tirzepatide. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is Tirzepatide approved?
Tirzepatide is authorised as a prescription medicine in the UK, EU and US under brand names. Research-grade material is not that medicine and must not be used in people or animals.
Key terms for Tirzepatide
Further reading
- BuyingHow to choose a research peptide supplier: a UK buyer's checklist8 min read
- BuyingPeptide price per mg: how to compare vials properly5 min read
- ComparisonSemaglutide vs tirzepatide vs retatrutide: the three incretin peptides compared7 min read
- MetabolicIncretin and amylin peptides explained: GLP-1, GIP, glucagon and amylin7 min read
Cite this page
peptide.wiki. (2026). Tirzepatide: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/tirzepatide