At a glance
- Class
- Thymosin beta-4 fragment
- Receptor targets
- Actin regulation (G-actin binding)
- Length
- Fragment (≈ 7 residues in the commonly cited form); full-length thymosin β4 is 43
- Molecular mass
- Varies by definition (full-length thymosin β4 ≈ 4.96 kDa)
- Origin
- Synthetic fragment of a human protein
- Research area
- Tissue repair & recovery
- Also known as
- Thymosin beta-4 fragment, Tβ4 fragment
What TB-500 is
Thymosin beta-4 is a 43-amino-acid protein that regulates actin, a core component of the cell's skeleton. 'TB-500' usually refers to a shorter synthetic piece based on its actin-binding region, although some suppliers use the label for other constructs.
Research interest centres on cell migration and wound-model endpoints. As with BPC-157, most of the data come from animal and cell studies.
What the research literature studies
- Actin binding and cell-migration assays
- Wound-model endpoints in cell culture and animal work
- Stability and identity of a fragment compared with the parent protein
Evidence rating: 1/5
Limited, preclinical or single-group. Preclinical and cell data. The exact construct varies between suppliers. See our methodology for how levels are assigned.
- 'TB-500' is not a single standardised molecule, so published studies on full-length thymosin β4 do not automatically apply.
- No adequately powered human trials of the fragment.
Regulatory status
TB-500 is not an approved medicine with the MHRA, EMA or FDA. Nordapep supplies it for in vitro laboratory research only.
Reviewed November 2026.
TB-500 at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare TB-500
TB-500 FAQ
Is TB-500 the same as thymosin beta-4?
Not exactly. Thymosin beta-4 is the 43-residue parent protein. TB-500 usually denotes a shorter synthetic fragment, but the label is used inconsistently, so always check the supplier's mass-spectrometry data.
Where can I buy TB-500 for research?
Nordapep does not currently list TB-500. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is TB-500 approved?
TB-500 is not an approved medicine with the MHRA, EMA or FDA. Nordapep supplies it for in vitro laboratory research only.
Key terms for TB-500
Cite this page
peptide.wiki. (2026). TB-500: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/tb-500