Thymosin alpha-1: Research Guide, Evidence & Price per mg

Thymosin alpha-1

Thymosin alpha-1 is a 28-amino-acid, N-acetylated peptide first isolated from calf thymus. As the synthetic drug thymalfasin it is approved in a number of countries, though not by the FDA. It is not the same molecule as thymosin beta-4 (TB-500).

Approved in some countries, not by the FDAImmune & inflammation research28-amino-acid thymic peptide with late-stage human data4/5

At a glance

4/5

Class: Thymic peptide (immunomodulator)
Receptor targets: Toll-like-receptor signalling, T-cell pathways
Length: 28 amino acids (N-acetylated)
Molecular mass: ≈ 3.11 kDa
Origin: Naturally occurring thymic peptide, produced synthetically
Research area: Immune & inflammation research
Also known as: Tα1, Thymalfasin

Peptide molecular weight calculator Certificate of Analysis checker Stock solution & dilution calculator

What Thymosin alpha-1 is

Thymosin alpha-1 derives from the precursor protein prothymosin alpha. Research focuses on how it influences toll-like-receptor signalling and T-cell responses.

Late-stage human trials exist, mainly in viral hepatitis, and results in other settings such as sepsis have been mixed. The name causes frequent confusion with TB-500, which comes from a different protein.

What the research literature studies

Toll-like-receptor and dendritic-cell signalling in vitro
T-cell maturation and cytokine readouts in cell models
Effect of N-terminal acetylation on stability and identification

Evidence rating: 4/5

Late-stage human trials. Late-stage human trials, mainly in hepatitis B. Results in other indications are mixed. See our methodology for how levels are assigned.

Most human data are in specific diseases and say nothing about research material.
Evidence for thymosin alpha-1 does not transfer to thymosin beta-4, and the reverse.

Regulatory status

Synthetic thymosin alpha-1 (thymalfasin) is authorised as a prescription medicine in a number of countries, including China. It is not approved by the FDA. Research-grade material is not that medicine and must not be used in people or animals.

Reviewed November 2026.

Thymosin alpha-1 at Nordapep: sizes and price per mg

Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.

Not currently listed at Nordapep.

Compare Thymosin alpha-1

Thymosin Alpha-1 vs TB-500 →Compare with anything else

Thymosin alpha-1 FAQ

Is thymosin alpha-1 the same as TB-500?

No. Thymosin alpha-1 is a 28-residue thymic peptide. TB-500 is a fragment of thymosin beta-4, an actin-binding protein. They share a family name but not structure or function. See the comparison page.

Where can I buy Thymosin alpha-1 for research?

Nordapep does not currently list Thymosin alpha-1. You can ask Nordapep about availability, or compare related compounds that are in stock.

Is Thymosin alpha-1 approved?

Key terms for Thymosin alpha-1

In vitro

Cite this page

peptide.wiki. (2026). Thymosin alpha-1: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/thymosin-alpha-1

Free to cite and link. Last reviewed November 2026.

For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.