At a glance
- Class
- Triple GIP / GLP-1 / glucagon agonist
- Receptor targets
- GIPR, GLP-1R, GCGR
- Length
- ≈ 40 amino acids (fatty-acid modified)
- Molecular mass
- ≈ 4.7 kDa
- Origin
- Synthetic
- Research area
- Metabolic & incretin research
- Also known as
- LY3437943
What Retatrutide is
Retatrutide (developed by Eli Lilly as LY3437943) is described as a triple agonist because one molecule activates the GIP, GLP-1 and glucagon receptors.
It is the newest of the three major incretin peptides and the one with the fastest-growing research interest. Because it is not yet an approved medicine, the published evidence is thinner and still accumulating.
What the research literature studies
- Triple-receptor signalling profile in cell-based assays
- How glucagon-receptor activity differs from GLP-1 and GIP activity
- Identity and purity analysis of a large modified peptide (HPLC and intact mass)
Evidence rating: 4/5
Late-stage human trials. Published phase 2 results and an ongoing phase 3 programme. Not yet approved. See our methodology for how levels are assigned.
- Long-term safety and efficacy data are still being generated.
- Treat any claim made before phase 3 completes as provisional.
Regulatory status
Retatrutide has not been approved by any regulator, including the MHRA, EMA and FDA. Research material is not a medicine and must not be used in people or animals.
Reviewed November 2026.
Retatrutide at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
| Size | Price | Per mg | Availability |
|---|---|---|---|
| 15mg | £185.31 | £12.35 | In stock |
| Size | Price | Per mg | Availability |
|---|---|---|---|
| 40mg | £329.91 | £8.25 | In stock |
| Size | Price | Per mg | Availability |
|---|---|---|---|
| 10mg | £63.40 | £6.34 | In stock |
| Size | Price | Per mg | Availability |
|---|---|---|---|
| 20mg | £101.77 | £5.09 | In stock |
Live Nordapep prices, refreshed hourly. Prices in GBP, excluding shipping; see Nordapep for the current price.
Compare Retatrutide
Retatrutide FAQ
Why is retatrutide called a triple agonist?
Because a single molecule activates three receptors: GIP, GLP-1 and glucagon.
Is retatrutide approved?
No. It is an investigational medicine. Nordapep supplies it for in vitro laboratory research only.
Where can I buy Retatrutide for research?
Retatrutide is listed at Nordapep with a batch-matched Certificate of Analysis, from £63.40. It is supplied for in vitro laboratory research only.
Key terms for Retatrutide
Further reading
Cite this page
peptide.wiki. (2026). Retatrutide: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/retatrutide