Glossary
GIP
Glucose-dependent insulinotropic polypeptide, an incretin hormone. Dual agonists such as tirzepatide activate both its receptor and the GLP-1 receptor.
Relevant compounds
Further reading
- Semaglutide vs tirzepatide vs retatrutide: the three incretin peptides compared
How the three best-known incretin research compounds differ in receptor targets, evidence and regulatory status, with links to each head-to-head comparison.
- Incretin and amylin peptides explained: GLP-1, GIP, glucagon and amylin
A plain-English map of the receptors behind semaglutide, tirzepatide, retatrutide, cagrilintide and the earlier GLP-1 analogues, and how each added a target.
See also
For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.