At a glance
- Class
- Non-selective melanocortin agonist
- Receptor targets
- MC1R, MC3R, MC4R, MC5R
- Length
- 7 amino acids (cyclic)
- Molecular mass
- ≈ 1.02 kDa
- Origin
- Synthetic alpha-MSH analogue
- Research area
- Melanocortin receptors
- Also known as
- MT-II, MT2
What Melanotan II is
Melanotan II is a cyclic analogue of alpha-MSH. It activates MC1R, MC3R, MC4R and MC5R without strong selectivity, which is what makes it a broad tool compound.
Its history is mainly as the parent of more selective analogues such as PT-141.
What the research literature studies
- Melanocortin-receptor subtype activity profiling
- Pigmentation pathways in cell and animal models
- Structure-activity work leading to selective analogues
Evidence rating: 2/5
Mostly animal and in vitro. Small early human studies and animal work. Never approved. See our methodology for how levels are assigned.
- Non-selective receptor activity limits how cleanly results can be interpreted.
Regulatory status
Melanotan II is not an approved medicine anywhere, and regulators including the MHRA have warned about unlicensed melanotan products. Nordapep supplies it for in vitro laboratory research only.
Reviewed November 2026.
Melanotan II at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
| Size | Price | Per mg | Availability |
|---|---|---|---|
| 10mg | £33.88 | £3.39 | In stock |
Live Nordapep prices, refreshed hourly. Prices in GBP, excluding shipping; see Nordapep for the current price.
Compare Melanotan II
Melanotan II FAQ
Is Melanotan II legal?
It is not an authorised medicine, and selling it for human use is prohibited in the UK. Nordapep supplies it for in vitro laboratory research only.
Where can I buy Melanotan II for research?
Melanotan II is listed at Nordapep with a batch-matched Certificate of Analysis, from £33.88. It is supplied for in vitro laboratory research only.
Is Melanotan II approved?
Melanotan II is not an approved medicine anywhere, and regulators including the MHRA have warned about unlicensed melanotan products. Nordapep supplies it for in vitro laboratory research only.
Key terms for Melanotan II
Further reading
Cite this page
peptide.wiki. (2026). Melanotan II: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/melanotan-2