At a glance
- Class
- Melanocortin receptor agonist
- Receptor targets
- MC4R (also MC1R)
- Length
- 7 amino acids (cyclic)
- Molecular mass
- ≈ 1.03 kDa
- Origin
- Synthetic, derived from melanotan II
- Research area
- Melanocortin receptors
- Also known as
- Bremelanotide
What PT-141 is
Bremelanotide is a metabolite-derived analogue of melanotan II that acts mainly on melanocortin receptors in the central nervous system, especially MC4R.
It is approved by the FDA for a narrow indication, which gives it a stronger evidence base than most peptides in this category.
What the research literature studies
- MC4R signalling and receptor-selectivity assays
- Central melanocortin pathways in animal models
- Cyclic peptide structure and stability
Evidence rating: 5/5
Approved drug, phase 3 trials. Approved in the US for one indication on the strength of phase 3 trials. See our methodology for how levels are assigned.
- Approval covers one indication in one region; it says nothing about other uses.
Regulatory status
Bremelanotide is FDA-approved as a prescription medicine for one indication. It has no MHRA or EMA authorisation at the time of writing. Research-grade material is not that medicine and must not be used in people or animals.
Reviewed November 2026.
PT-141 at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare PT-141
PT-141 FAQ
PT-141 or Melanotan II?
PT-141 is derived from melanotan II but is more selective for central melanocortin receptors. See the comparison page.
Where can I buy PT-141 for research?
Nordapep does not currently list PT-141. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is PT-141 approved?
Bremelanotide is FDA-approved as a prescription medicine for one indication. It has no MHRA or EMA authorisation at the time of writing. Research-grade material is not that medicine and must not be used in people or animals.
Key terms for PT-141
Further reading
Cite this page
peptide.wiki. (2026). PT-141: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/pt-141