Skip to content
Every compound links to batch-tested stock at Nordapep, with a Certificate of Analysis per batch.
peptide.wiki

Liraglutide

Liraglutide is an acylated GLP-1 analogue with a half-life of about 13 hours. It is an approved medicine and the older sibling of semaglutide in the incretin literature.

Approved prescription medicineMetabolic & incretin researchFirst-generation acylated GLP-1 receptor agonist5/55/5

At a glance

5/55/5
Class
GLP-1 receptor agonist
Receptor targets
GLP-1R
Length
31 amino acids (acylated GLP-1 analogue)
Molecular mass
≈ 3.75 kDa
Origin
Analogue of human GLP-1
Research area
Metabolic & incretin research
Also known as
–

What Liraglutide is

Liraglutide is built on human GLP-1 with one amino-acid substitution and a C16 fatty acid attached through a glutamic-acid spacer. The fatty acid lets it bind albumin in blood, which protects it from rapid clearance. Semaglutide later extended the same design idea.

Because it has been in clinical use since 2009, liraglutide has one of the longest published records among GLP-1 agonists, and it is a common comparator in studies of newer incretin peptides.

What the research literature studies

  • GLP-1 receptor binding and signalling in cell-based assays
  • Albumin binding and the effect of fatty-acid acylation on peptide stability
  • Use as a comparator when characterising newer incretin analogues

Evidence rating: 5/5

Approved drug, phase 3 trials. Approved medicine backed by large randomised programmes, including cardiovascular outcome trials. See our methodology for how levels are assigned.

  • Outcome data come from the branded medicines, not from research-grade material.
  • Acylated peptides need intact-mass analysis, not only HPLC purity, to confirm identity.

Regulatory status

Liraglutide is authorised as a prescription medicine by the MHRA, EMA and FDA under several brand names. Research-grade material is not that medicine, is not evaluated by any regulator, and must not be used in people or animals.

Reviewed November 2026.

Liraglutide at Nordapep: sizes and price per mg

Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.

Not currently listed at Nordapep.

Compare Liraglutide

Liraglutide FAQ

How does liraglutide differ from semaglutide?

Both are acylated GLP-1 analogues that act on the GLP-1 receptor only. Semaglutide has a different N-terminal substitution and a longer fatty-diacid linker, which gives it a half-life of about a week compared with roughly 13 hours for liraglutide. See the comparison page.

Is liraglutide a peptide or a protein?

A peptide. It has 31 amino acids plus a fatty-acid side chain.

Where can I buy Liraglutide for research?

Nordapep does not currently list Liraglutide. You can ask Nordapep about availability, or compare related compounds that are in stock.

Is Liraglutide approved?

Liraglutide is authorised as a prescription medicine by the MHRA, EMA and FDA under several brand names. Research-grade material is not that medicine, is not evaluated by any regulator, and must not be used in people or animals.

Key terms for Liraglutide

Further reading

Cite this page

peptide.wiki. (2026). Liraglutide: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/liraglutide
Free to cite and link. Last reviewed November 2026.
For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.

Related compounds