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Ipamorelin vs GHRP-6

Both activate the ghrelin (GHS) receptor. GHRP-6 is a six-residue, first-generation compound. Ipamorelin is a five-residue compound developed later with a more selective profile.

Selective ghrelin-receptor agonist

Choose Ipamorelin if

  • ✓ You need a more selective ghrelin-receptor agonist
  • ✓ You are comparing newer and older secretagogues
Buy Ipamorelin

First-generation ghrelin-receptor agonist

Choose GHRP-6 if

  • ✓ You want the classic first-generation reference compound
  • ✓ You are replicating older GH secretagogue literature
Buy GHRP-6

Side-by-side specification

CompareIpamorelin
Selective ghrelin-receptor agonist
GHRP-6
First-generation ghrelin-receptor agonist
ClassGhrelin-receptor (GHS-R) agonistGhrelin-receptor (GHS-R) agonist
Research areaGH axisGH axis
Receptor targetsGHS-R1aGHS-R1a
Length5 amino acids6 amino acids
Molecular mass≈ 712 Da≈ 873 Da
OriginSyntheticSynthetic, enkephalin-derived
Evidence level
2/5
Mostly animal and in vitro
2/5
Mostly animal and in vitro
Regulatory statusNot approvedNot approved
Nordapep fromNot listedNot listed
Best price per mgNot listedNot listed
View Ipamorelin at Nordapep →View GHRP-6 at Nordapep →

What separates them

In the published studies GHRP-6 also affects cortisol, prolactin and feeding behaviour, while ipamorelin shows little effect on cortisol or prolactin. Neither is approved and both rest on small, older human datasets.

Read the full guides for Ipamorelin and GHRP-6, or add a third compound in the comparison tool.

Studying both?
Nordapep lists each with its own batch CoA. Its research stacks bundle common pairings.
See stacks at Nordapep

FAQ

Is GHRP-6 the same as GHRP-2?

No. They are related but different six-residue peptides.

Which has more literature?

GHRP-6 has the longer record, but much of it is decades old.

Are Ipamorelin and GHRP-6 approved medicines?

Ipamorelin: Not approved. GHRP-6: Not approved. Research-grade material of either is not a medicine and is supplied for in vitro research only.

Where can I buy Ipamorelin and GHRP-6?

Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.

More comparisons

For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.