Tesamorelin vs CJC-1295
Both are GHRH analogues acting on the same pituitary receptor. Tesamorelin keeps the full 44-residue GHRH sequence and adds an N-terminal hexenoyl group. CJC-1295 is built on the first 29 residues and comes in versions with and without a drug affinity complex (DAC) that differ greatly in half-life.
Stabilised full-length GHRH analogue
Choose Tesamorelin if
- ✓ You want an approved, well-documented GHRH analogue
- ✓ You are comparing full-length and truncated GHRH sequences
GHRH analogue
Choose CJC-1295 if
- ✓ You are studying the effect of DAC modification on half-life
- ✓ Your design pairs a GHRH analogue with a ghrelin-receptor agonist
Side-by-side specification
| Compare | Tesamorelin Stabilised full-length GHRH analogue | CJC-1295 GHRH analogue |
|---|---|---|
| Class | GHRH receptor agonist | GHRH receptor agonist |
| Research area | GH axis | GH axis |
| Receptor targets | GHRH-R | GHRH-R |
| Length | 44 amino acids (hexenoyl-modified) | 29 amino acids |
| Molecular mass | ≈ 5.14 kDa | ≈ 3.37 kDa (without DAC) |
| Origin | Synthetic analogue of human GHRH | Synthetic analogue of human GHRH |
| Evidence level | 5/5 Approved drug, phase 3 trials | 2/5 Mostly animal and in vitro |
| Regulatory status | Approved in the US for one indication | Not approved |
| Nordapep from | Not listed | Not listed |
| Best price per mg | Not listed | Not listed |
| View Tesamorelin at Nordapep → | View CJC-1295 at Nordapep → |
What separates them
Tesamorelin is an FDA-approved medicine for one indication with a phase 3 evidence base. CJC-1295 has never been approved and has only small early human datasets. Tesamorelin is the better-documented benchmark, while CJC-1295 is more often studied alongside ghrelin-receptor agonists.
Read the full guides for Tesamorelin and CJC-1295, or add a third compound in the comparison tool.
FAQ
Do they act on the same receptor?
Yes. Both act on the GHRH receptor on pituitary cells.
Why is CJC-1295 ambiguous?
The name is used for both the DAC and no-DAC forms, which are different molecules.
Are Tesamorelin and CJC-1295 approved medicines?
Tesamorelin: Approved in the US for one indication. CJC-1295: Not approved. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy Tesamorelin and CJC-1295?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
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Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.