Sermorelin vs CJC-1295
Both act on the GHRH receptor. Sermorelin is the native 1-29 fragment of GHRH and has a half-life of minutes. CJC-1295 is a modified analogue engineered for greater stability and a longer duration.
Shortest fully active fragment of GHRH
Choose Sermorelin if
- ✓ You need the unmodified native-sequence fragment
- ✓ You want a baseline for GHRH analogue stability studies
GHRH analogue
Choose CJC-1295 if
- ✓ Your question is about engineered stability
- ✓ You are comparing GHRH analogues with different half-lives
Side-by-side specification
| Compare | Sermorelin Shortest fully active fragment of GHRH | CJC-1295 GHRH analogue |
|---|---|---|
| Class | GHRH receptor agonist | GHRH receptor agonist |
| Research area | GH axis | GH axis |
| Receptor targets | GHRH receptor | GHRH-R |
| Length | 29 amino acids (C-terminal amide) | 29 amino acids |
| Molecular mass | ≈ 3.36 kDa | ≈ 3.37 kDa (without DAC) |
| Origin | Synthetic fragment of human GHRH | Synthetic analogue of human GHRH |
| Evidence level | 3/5 Early human trials | 2/5 Mostly animal and in vitro |
| Regulatory status | Formerly approved (discontinued) | Not approved |
| Nordapep from | Not listed | Not listed |
| Best price per mg | Not listed | Not listed |
| View Sermorelin at Nordapep → | View CJC-1295 at Nordapep → |
What separates them
For research, sermorelin is the natural baseline for GHRH-receptor work and has a history as an approved product. CJC-1295 is the choice when a longer-acting GHRH analogue is the subject.
Read the full guides for Sermorelin and CJC-1295, or add a third compound in the comparison tool.
FAQ
Do they act on the same receptor?
Yes, both act on the pituitary GHRH receptor.
Why is sermorelin's half-life so short?
It is the unmodified native sequence, so enzymes in the circulation break it down within minutes.
Are Sermorelin and CJC-1295 approved medicines?
Sermorelin: Formerly approved (discontinued). CJC-1295: Not approved. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy Sermorelin and CJC-1295?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
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Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.