GHRP-2 vs GHRP-6
Both are six-residue peptides that activate the ghrelin (GHS-R1a) receptor, and both sit in the original growth hormone releasing peptide family. They differ in sequence and in how they affect other pituitary hormones and appetite signalling in published studies.
Synthetic hexapeptide ghrelin-receptor agonist
Choose GHRP-2 if
- ✓ You want the follow-on with a diagnostic approval
- ✓ Your question concerns relative potency within the family
First-generation ghrelin-receptor agonist
Choose GHRP-6 if
- ✓ You need the original reference GHRP
- ✓ You are comparing appetite-related signalling
Side-by-side specification
| Compare | GHRP-2 Synthetic hexapeptide ghrelin-receptor agonist | GHRP-6 First-generation ghrelin-receptor agonist |
|---|---|---|
| Class | Growth hormone releasing peptide (GHRP) | Ghrelin-receptor (GHS-R) agonist |
| Research area | GH axis | GH axis |
| Receptor targets | GHS-R1a (ghrelin receptor) | GHS-R1a |
| Length | 6 amino acids (contains D-residues) | 6 amino acids |
| Molecular mass | ≈ 0.82 kDa | ≈ 873 Da |
| Origin | Synthetic | Synthetic, enkephalin-derived |
| Evidence level | 3/5 Early human trials | 2/5 Mostly animal and in vitro |
| Regulatory status | Approved in Japan as a diagnostic only | Not approved |
| Nordapep from | Not listed | Not listed |
| Best price per mg | Not listed | Not listed |
| View GHRP-2 at Nordapep → | View GHRP-6 at Nordapep → |
What separates them
For research, GHRP-6 is the original reference compound and GHRP-2 is the more potent follow-on. Only GHRP-2 has a regulatory approval, as a diagnostic agent in Japan.
Read the full guides for GHRP-2 and GHRP-6, or add a third compound in the comparison tool.
FAQ
Do they act on the same receptor?
Yes. Both act on the ghrelin (GHS-R1a) receptor.
Are either approved?
GHRP-2 is approved in Japan solely as a diagnostic agent. GHRP-6 has no approval.
Are GHRP-2 and GHRP-6 approved medicines?
GHRP-2: Approved in Japan as a diagnostic only. GHRP-6: Not approved. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy GHRP-2 and GHRP-6?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
More comparisons
Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.