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GHRP-2

GHRP-2 is a six-residue peptide that activates the ghrelin (GHS-R1a) receptor. It is approved in Japan solely as a diagnostic agent and is prohibited in sport.

Approved in Japan as a diagnostic onlyGrowth-hormone axisSynthetic hexapeptide ghrelin-receptor agonist3/53/5

At a glance

3/53/5
Class
Growth hormone releasing peptide (GHRP)
Receptor targets
GHS-R1a (ghrelin receptor)
Length
6 amino acids (contains D-residues)
Molecular mass
≈ 0.82 kDa
Origin
Synthetic
Research area
Growth-hormone axis
Also known as
Pralmorelin, KP-102

What GHRP-2 is

GHRP-2 (pralmorelin) belongs to the growth hormone releasing peptide family. It is a hexapeptide containing D-amino acids, which make it resistant to peptidases, and it acts on the ghrelin receptor rather than the GHRH receptor.

It is often discussed alongside GHRP-6, hexarelin and ipamorelin, which differ in how selective they are for growth hormone release compared with other pituitary hormones. Its one regulatory approval is as a single-dose diagnostic in Japan.

What the research literature studies

  • Ghrelin-receptor binding and calcium signalling in pituitary and cell models
  • Comparison of GHRP family members for selectivity of growth hormone release
  • Resistance to peptidase degradation conferred by D-amino acid substitutions

Evidence rating: 3/5

Early human trials. Human pharmacology and diagnostic-use studies; no approved therapeutic use. See our methodology for how levels are assigned.

  • The approved use is a one-off diagnostic test, so it says little about any other context.
  • Compared with more selective members of the family, it also affects other pituitary hormones.

Regulatory status

GHRP-2 is approved in Japan as a diagnostic agent for assessing growth hormone secretion, and has no therapeutic approval from the MHRA, EMA or FDA. It is prohibited under anti-doping rules. Research-grade material must not be used in people or animals.

Reviewed November 2026.

GHRP-2 at Nordapep: sizes and price per mg

Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.

Not currently listed at Nordapep.

Compare GHRP-2

GHRP-2 FAQ

How does GHRP-2 differ from GHRP-6?

Both activate the ghrelin receptor. They differ in sequence and in their effect profile; see the side-by-side comparison for structure and evidence level.

Is GHRP-2 approved?

Only in Japan, and only as a diagnostic agent. It is not approved as a treatment anywhere that we are aware of.

Where can I buy GHRP-2 for research?

Nordapep does not currently list GHRP-2. You can ask Nordapep about availability, or compare related compounds that are in stock.

Key terms for GHRP-2

Cite this page

peptide.wiki. (2026). GHRP-2: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/ghrp-2
Free to cite and link. Last reviewed November 2026.
For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.

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