At a glance
- Class
- Ghrelin-receptor (GHS-R) agonist
- Receptor targets
- GHS-R1a
- Length
- 6 amino acids
- Molecular mass
- ≈ 873 Da
- Origin
- Synthetic, enkephalin-derived
- Research area
- Growth-hormone axis
- Also known as
- Growth hormone-releasing peptide-6
What GHRP-6 is
GHRP-6 was developed in the 1980s from enkephalin-derived peptides, before the ghrelin receptor or its natural ligand had been identified. Work on the GHRPs helped lead to the cloning of the receptor and the discovery of ghrelin.
Compared with ipamorelin, GHRP-6 is less selective in the published studies, which report effects beyond GH release, including on cortisol, prolactin and feeding behaviour. It is generally treated as a reference compound rather than a precise tool.
What the research literature studies
- Ghrelin-receptor binding and signalling
- Selectivity comparisons across GH secretagogues
- Structure-activity work on peptides containing D-amino acids
Evidence rating: 2/5
Mostly animal and in vitro. Small human studies, mostly decades old. Never approved. See our methodology for how levels are assigned.
- Little recent independent work: much of the literature is decades old.
- Its broader hormonal effects make it a poor model for a selective GH signal.
Regulatory status
GHRP-6 is not an approved medicine with the MHRA, EMA or FDA. Research-grade material must not be used in people or animals.
Reviewed November 2026.
GHRP-6 at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare GHRP-6
GHRP-6 FAQ
Is GHRP-6 the same as GHRP-2?
No. They are related six-residue peptides with different sequences and different published selectivity. Check the exact name on any certificate of analysis.
GHRP-6 or ipamorelin?
Ipamorelin was developed later with a more selective profile. See the comparison page.
Where can I buy GHRP-6 for research?
Nordapep does not currently list GHRP-6. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is GHRP-6 approved?
GHRP-6 is not an approved medicine with the MHRA, EMA or FDA. Research-grade material must not be used in people or animals.
Key terms for GHRP-6
Further reading
Cite this page
peptide.wiki. (2026). GHRP-6: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/ghrp-6