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Tesamorelin

Tesamorelin is a 44-amino-acid analogue of growth-hormone-releasing hormone with an N-terminal hexenoyl group. It is an FDA-approved medicine for one indication.

Approved in the US for one indicationGrowth-hormone axisStabilised full-length GHRH analogue5/55/5

At a glance

5/55/5
Class
GHRH receptor agonist
Receptor targets
GHRH-R
Length
44 amino acids (hexenoyl-modified)
Molecular mass
≈ 5.14 kDa
Origin
Synthetic analogue of human GHRH
Research area
Growth-hormone axis
Also known as
Egrifta

What Tesamorelin is

Tesamorelin keeps all 44 residues of human GHRH and adds a trans-3-hexenoyl group to the N-terminus, which slows enzymatic breakdown.

That makes it structurally different from CJC-1295, a shortened 29-residue GHRH fragment. Researchers use tesamorelin as the approved benchmark when comparing GHRH analogues.

What the research literature studies

  • GHRH-receptor binding and cAMP signalling
  • Effect of N-terminal modification on enzymatic stability
  • Comparison of full-length and truncated GHRH analogues

Evidence rating: 5/5

Approved drug, phase 3 trials. Approved medicine backed by phase 3 trials in its labelled indication. See our methodology for how levels are assigned.

  • Approval covers one indication and is not evidence for any other use.
  • Long peptides are harder to synthesise cleanly, so intact-mass confirmation matters.

Regulatory status

Tesamorelin is FDA-approved as a prescription medicine for one indication. That approval covers one use in one region. Research-grade material is not that medicine and must not be used in people or animals.

Reviewed November 2026.

Tesamorelin at Nordapep: sizes and price per mg

Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.

Not currently listed at Nordapep.

Compare Tesamorelin

Tesamorelin FAQ

How does tesamorelin differ from CJC-1295?

Tesamorelin is the full 44-residue GHRH sequence with an N-terminal hexenoyl group. CJC-1295 is based on the first 29 residues. Both act on the GHRH receptor. See the comparison page.

Where can I buy Tesamorelin for research?

Nordapep does not currently list Tesamorelin. You can ask Nordapep about availability, or compare related compounds that are in stock.

Is Tesamorelin approved?

Tesamorelin is FDA-approved as a prescription medicine for one indication. That approval covers one use in one region. Research-grade material is not that medicine and must not be used in people or animals.

Key terms for Tesamorelin

Further reading

Cite this page

peptide.wiki. (2026). Tesamorelin: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/tesamorelin
Free to cite and link. Last reviewed November 2026.
For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.

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