Mazdutide vs Survodutide
Both compounds activate the GLP-1 and glucagon receptors, but they are different molecules. Mazdutide is an oxyntomodulin analogue developed in China and approved there for obesity; survodutide is built on a glucagon-like backbone and remains investigational.
GLP-1 and glucagon receptor dual agonist, approved in China
Choose Mazdutide if
- ✓ Your question concerns oxyntomodulin-based design
- ✓ You want the compound with a regional approval
Investigational GLP-1 and glucagon receptor dual agonist
Choose Survodutide if
- ✓ Your question concerns a glucagon-based backbone
- ✓ You are following the international phase 3 programme
Side-by-side specification
| Compare | Mazdutide GLP-1 and glucagon receptor dual agonist, approved in China | Survodutide Investigational GLP-1 and glucagon receptor dual agonist |
|---|---|---|
| Class | Dual GLP-1 / glucagon receptor agonist (oxyntomodulin analogue) | Dual GLP-1 / glucagon receptor agonist |
| Research area | Metabolic | Metabolic |
| Receptor targets | GLP-1R, GCGR | GLP-1R, GCGR |
| Length | Modified oxyntomodulin-based peptide (fatty-acid conjugated) | ≈ 29 amino acids (acylated, one non-coded residue) |
| Molecular mass | Not fully published (large acylated peptide, several kDa) | ≈ 4.23 kDa |
| Origin | Synthetic, oxyntomodulin-based sequence | Synthetic, glucagon-based sequence |
| Evidence level | 4/5 Late-stage human trials | 4/5 Late-stage human trials |
| Regulatory status | Approved in China | Investigational |
| Nordapep from | Not listed | Not listed |
| Best price per mg | Not listed | Not listed |
| View Mazdutide at Nordapep → | View Survodutide at Nordapep → |
What separates them
For research, the comparison is useful because it holds the receptor pair constant while the backbone and fatty-acid design differ. Most human data for mazdutide come from Chinese study populations, while survodutide's phase 3 programme is international.
Read the full guides for Mazdutide and Survodutide, or add a third compound in the comparison tool.
FAQ
Do they act on the same receptors?
Yes. Both activate the GLP-1 and glucagon receptors.
Which is further along in development?
Mazdutide has a regional approval in China; survodutide is still investigational.
Are Mazdutide and Survodutide approved medicines?
Mazdutide: Approved in China. Survodutide: Investigational. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy Mazdutide and Survodutide?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
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Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.