At a glance
- Class
- Dual GLP-1 / glucagon receptor agonist (oxyntomodulin analogue)
- Receptor targets
- GLP-1R, GCGR
- Length
- Modified oxyntomodulin-based peptide (fatty-acid conjugated)
- Molecular mass
- Not fully published (large acylated peptide, several kDa)
- Origin
- Synthetic, oxyntomodulin-based sequence
- Research area
- Metabolic & incretin research
- Also known as
- IBI362, LY3305677
What Mazdutide is
Mazdutide originated in Eli Lilly's GLP-1/glucagon co-agonist research and was developed in China by Innovent Biologics as IBI362. It is an analogue of oxyntomodulin, a natural gut hormone that activates both the GLP-1 and glucagon receptors.
Its main research interest is the glucagon component, which is studied for its effects on energy expenditure and liver fat alongside the appetite-related GLP-1 signal. Most published human data come from Chinese study populations.
What the research literature studies
- GLP-1 and glucagon receptor signalling in cell-based assays
- Oxyntomodulin analogues and the role of glucagon-receptor activity in rodent models
- Identity and purity analysis of a large modified peptide (HPLC and intact mass)
Evidence rating: 4/5
Late-stage human trials. Phase 3 data from Chinese populations and a regional approval. Limited data outside China. See our methodology for how levels are assigned.
- Human data are concentrated in Chinese study populations and may not generalise.
- Head-to-head evidence against other incretin peptides is still limited.
Regulatory status
Mazdutide has been approved by China's NMPA for obesity. It has not been approved by the MHRA, EMA or FDA. Research material is not that medicine and must not be used in people or animals.
Reviewed November 2026.
Mazdutide at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare Mazdutide
Mazdutide FAQ
Is mazdutide the same as survodutide?
No. Both activate the GLP-1 and glucagon receptors, but they are different molecules from different developers, with different backbones and different regulatory histories.
Is mazdutide approved in the UK or EU?
No. It has a regional approval in China only. Research-grade material is for in vitro laboratory work only.
Where can I buy Mazdutide for research?
Nordapep does not currently list Mazdutide. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is Mazdutide approved?
Mazdutide has been approved by China's NMPA for obesity. It has not been approved by the MHRA, EMA or FDA. Research material is not that medicine and must not be used in people or animals.
Key terms for Mazdutide
Cite this page
peptide.wiki. (2026). Mazdutide: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/mazdutide