Tesamorelin vs Ipamorelin
These two differ in almost everything except the cell type they act on. Tesamorelin is a 44-residue stabilised GHRH analogue acting on the GHRH receptor. Ipamorelin is a five-residue synthetic peptide acting on the ghrelin receptor.
Stabilised full-length GHRH analogue
Choose Tesamorelin if
- ✓ You are studying GHRH-receptor signalling
- ✓ You need a compound with an extensive clinical literature
Selective ghrelin-receptor agonist
Choose Ipamorelin if
- ✓ You are studying ghrelin-receptor signalling
- ✓ You want a short peptide that is simple to characterise by mass spectrometry
Side-by-side specification
| Compare | Tesamorelin Stabilised full-length GHRH analogue | Ipamorelin Selective ghrelin-receptor agonist |
|---|---|---|
| Class | GHRH receptor agonist | Ghrelin-receptor (GHS-R) agonist |
| Research area | GH axis | GH axis |
| Receptor targets | GHRH-R | GHS-R1a |
| Length | 44 amino acids (hexenoyl-modified) | 5 amino acids |
| Molecular mass | ≈ 5.14 kDa | ≈ 712 Da |
| Origin | Synthetic analogue of human GHRH | Synthetic |
| Evidence level | 5/5 Approved drug, phase 3 trials | 2/5 Mostly animal and in vitro |
| Regulatory status | Approved in the US for one indication | Not approved |
| Nordapep from | — | — |
| Best price per mg | — | — |
| Browse Nordapep → | Browse Nordapep → |
What separates them
For research, tesamorelin is the well-characterised option with approved-medicine data. Ipamorelin is the small, selective ghrelin-receptor agonist, rated lower because its published human data are limited.
Read the full guides for Tesamorelin and Ipamorelin, or add a third compound in the comparison tool.
FAQ
Why are they often mentioned together?
Because the GHRH receptor and the ghrelin receptor are two separate inputs to the same pituitary cells, so researchers compare one agonist from each class.
How do their sizes compare?
Tesamorelin is about 5.14 kDa and ipamorelin about 712 Da, roughly a sevenfold difference.
Are Tesamorelin and Ipamorelin approved medicines?
Tesamorelin: Approved in the US for one indication. Ipamorelin: Not approved. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy Tesamorelin and Ipamorelin?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
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Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.