AOD-9604 vs Tesamorelin
Both names come up in growth-hormone research, but they work at different points. Tesamorelin acts on the GHRH receptor and so stimulates the pituitary's own growth hormone release. AOD-9604 is a modified fragment of the growth hormone molecule itself, and published studies report that it does not act through the growth hormone receptor.
Modified fragment of the growth hormone tail
Choose AOD-9604 if
- ✓ You are studying fragments of the growth hormone C-terminus
- ✓ Your question is about lipolysis models in rodents
Stabilised full-length GHRH analogue
Choose Tesamorelin if
- ✓ You need a compound that acts through the GHRH receptor
- ✓ You want strong clinical evidence behind the reference compound
Side-by-side specification
| Compare | AOD-9604 Modified fragment of the growth hormone tail | Tesamorelin Stabilised full-length GHRH analogue |
|---|---|---|
| Class | Growth hormone fragment | GHRH receptor agonist |
| Research area | Metabolic | GH axis |
| Receptor targets | Not fully defined (proposed β3-adrenergic-linked lipolysis in rodents) | GHRH-R |
| Length | 16 amino acids (modified fragment, with N-terminal tyrosine) | 44 amino acids (hexenoyl-modified) |
| Molecular mass | ≈ 1.82 kDa | ≈ 5.14 kDa |
| Origin | Synthetic, derived from human growth hormone | Synthetic analogue of human GHRH |
| Evidence level | 2/5 Mostly animal and in vitro | 5/5 Approved drug, phase 3 trials |
| Regulatory status | Not approved | Approved in the US for one indication |
| Nordapep from | — | — |
| Best price per mg | — | — |
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What separates them
The evidence gap is wide. Tesamorelin is an approved medicine in the US for one indication, rated 5. AOD-9604 did not show efficacy in its main clinical trial and is rated 2.
Read the full guides for AOD-9604 and Tesamorelin, or add a third compound in the comparison tool.
FAQ
Is AOD-9604 a growth hormone secretagogue?
No. It is a fragment of growth hormone, not a compound that triggers its release. Tesamorelin is the secretagogue of the two.
Is either approved?
Tesamorelin is approved in the US for one indication. AOD-9604 is not approved as a medicine.
Are AOD-9604 and Tesamorelin approved medicines?
AOD-9604: Not approved. Tesamorelin: Approved in the US for one indication. Research-grade material of either is not a medicine and is supplied for in vitro research only.
Where can I buy AOD-9604 and Tesamorelin?
Nordapep lists compounds with a Certificate of Analysis matched to the batch reference. Check each compound page for current availability.
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Where to buy
Why we send researchers to Nordapep
Comparing compounds is only half the job. The other half is knowing the vial contains what the label says. Nordapep publishes batch documentation for every compound it sells.
Browse the Nordapep catalogue →Each batch reference on the label matches its CoA, so you can check what is in the vial.
Enter the batch reference from your vial into Nordapep's batch-verification tool.
Purity is reported by RP-HPLC, the standard method for peptides of this size.
Bundled stacks for common comparisons, plus tiered pricing for volume orders.