At a glance
- Class
- Growth hormone fragment
- Receptor targets
- Not fully defined (proposed β3-adrenergic-linked lipolysis in rodents)
- Length
- 16 amino acids (modified fragment, with N-terminal tyrosine)
- Molecular mass
- ≈ 1.82 kDa
- Origin
- Synthetic, derived from human growth hormone
- Research area
- Metabolic & incretin research
- Also known as
- Tyr-hGH fragment 177-191, Anti-Obesity Drug 9604
What AOD-9604 is
In the 1990s, researchers found that a short C-terminal piece of growth hormone reproduced anti-lipogenic activity in rodent fat tissue. AOD-9604 was developed from that fragment, with a tyrosine added for stability, as a candidate anti-obesity compound.
The compound reached phase 2b human trials, where it failed to beat placebo on weight loss, and the obesity programme was discontinued. It has since been classed as a food ingredient in some jurisdictions, and is prohibited in sport. It is often confused with the unmodified fragment 176-191, which has even less human data.
What the research literature studies
- Lipolysis and lipogenesis in adipose tissue models
- Comparisons with intact growth hormone in rodents
- Structure-activity work on growth hormone C-terminal fragments
Evidence rating: 2/5
Mostly animal and in vitro. Rodent studies plus human trials that did not show clear benefit. Never approved as a medicine. See our methodology for how levels are assigned.
- Human obesity trials did not show a clear effect, so animal results should not be extrapolated.
- Often sold interchangeably with unmodified fragment 176-191, which is a different molecule.
Regulatory status
AOD-9604 is not an approved medicine, and its regulatory classification varies between countries. It is prohibited under anti-doping rules. Research-grade material must not be used in people or animals.
Reviewed November 2026.
AOD-9604 at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare AOD-9604
AOD-9604 FAQ
Is AOD-9604 the same as fragment 176-191?
Not exactly. AOD-9604 is a modified version, with an added tyrosine and a slightly different span, so the two should not be treated as interchangeable.
Does AOD-9604 act like growth hormone?
It was designed not to. The idea was to keep fat-metabolism activity without growth hormone receptor effects, although human trials did not confirm a benefit.
Where can I buy AOD-9604 for research?
Nordapep does not currently list AOD-9604. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is AOD-9604 approved?
AOD-9604 is not an approved medicine, and its regulatory classification varies between countries. It is prohibited under anti-doping rules. Research-grade material must not be used in people or animals.
Key terms for AOD-9604
Cite this page
peptide.wiki. (2026). AOD-9604: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/aod-9604