Peptide comparison tool
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| Compare | Semaglutide Long-acting GLP-1 receptor agonist | Tirzepatide Dual GIP and GLP-1 receptor agonist | Retatrutide Investigational GIP, GLP-1 and glucagon triple agonist |
|---|---|---|---|
| Class | GLP-1 receptor agonist | Dual GIP / GLP-1 receptor agonist | Triple GIP / GLP-1 / glucagon agonist |
| Research area | Metabolic | Metabolic | Metabolic |
| Receptor targets | GLP-1R | GIPR, GLP-1R | GIPR, GLP-1R, GCGR |
| Length | 31 amino acids (acylated GLP-1 analogue) | 39 amino acids (acylated) | ≈ 40 amino acids (fatty-acid modified) |
| Molecular mass | ≈ 4.11 kDa | ≈ 4.81 kDa | ≈ 4.7 kDa |
| Origin | Synthetic analogue of human GLP-1 | Synthetic, GIP-based sequence | Synthetic |
| Evidence level | 5/5 Approved drug, phase 3 trials | 5/5 Approved drug, phase 3 trials | 4/5 Late-stage human trials |
| Regulatory status | Approved prescription medicine | Approved prescription medicine | Investigational |
| Nordapep from | Not listed | Not listed | £63.40 |
| Best price per mg | Not listed | Not listed | £5.09/mg |
| View Semaglutide at Nordapep → | View Tirzepatide at Nordapep → | View Retatrutide at Nordapep → |
All in-depth comparisons
Semaglutide vs Tirzepatide →Tirzepatide vs Retatrutide →Semaglutide vs Retatrutide →BPC-157 vs TB-500 →CJC-1295 vs Ipamorelin →PT-141 vs Melanotan II →Semax vs Selank →Liraglutide vs Semaglutide →Semaglutide vs Cagrilintide →Tesamorelin vs CJC-1295 →Ipamorelin vs GHRP-6 →Afamelanotide vs Melanotan II →Setmelanotide vs PT-141 →MOTS-c vs SS-31 →Thymosin Alpha-1 vs TB-500 →Exenatide vs Liraglutide →Sermorelin vs CJC-1295 →Hexarelin vs GHRP-6 →Pramlintide vs Cagrilintide →Survodutide vs Retatrutide →Mazdutide vs Survodutide →GHRP-2 vs GHRP-6 →
For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.