At a glance
- Class
- GLP-2 receptor agonist
- Receptor targets
- GLP-2R
- Length
- 33 amino acids
- Molecular mass
- ≈ 3.75 kDa
- Origin
- Recombinant analogue of human GLP-2
- Research area
- Metabolic & incretin research
- Also known as
- –
What Teduglutide is
Teduglutide differs from native GLP-2 by a single amino-acid substitution near the N-terminus, which makes it resistant to cleavage by the enzyme DPP-4 and lengthens its half-life.
In research it is used as the benchmark GLP-2 receptor agonist, mainly in intestinal-epithelium and nutrient-absorption models. It is a close relative of the GLP-1 peptides but acts on a different receptor.
What the research literature studies
- GLP-2 receptor signalling in cell models
- Intestinal-epithelium growth and barrier biology in animal models
- Effect of a DPP-4-resistant substitution on peptide half-life
Evidence rating: 5/5
Approved drug, phase 3 trials. Approved medicine with randomised phase 3 trials in its authorised indication. See our methodology for how levels are assigned.
- Most outcome data come from the branded medicine, not from research-grade material.
- Findings from intestinal models should not be extrapolated beyond the model.
Regulatory status
Teduglutide is authorised as a prescription medicine by the EMA and the FDA under brand names. Laboratory research material is not that medicine and must not be used in people or animals.
Reviewed November 2026.
Teduglutide at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare Teduglutide
Teduglutide FAQ
How does GLP-2 differ from GLP-1?
Both come from the same precursor, proglucagon, but they act on different receptors and have different reported roles. GLP-1 is studied mainly for glucose and appetite signalling, GLP-2 for intestinal biology.
Why is teduglutide longer-lasting than native GLP-2?
A single residue change protects it from the enzyme DPP-4, which otherwise cleaves native GLP-2 within minutes.
Where can I buy Teduglutide for research?
Nordapep does not currently list Teduglutide. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is Teduglutide approved?
Teduglutide is authorised as a prescription medicine by the EMA and the FDA under brand names. Laboratory research material is not that medicine and must not be used in people or animals.
Key terms for Teduglutide
Cite this page
peptide.wiki. (2026). Teduglutide: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/teduglutide