At a glance
- Class
- GnRH receptor agonist (native sequence)
- Receptor targets
- GnRH receptor
- Length
- 10 amino acids (pyroglutamyl N-terminus, amidated C-terminus)
- Molecular mass
- ≈ 1.18 kDa
- Origin
- Synthetic copy of the human hormone
- Research area
- Reproductive & neuroendocrine
- Also known as
- GnRH, LHRH
What Gonadorelin is
Gonadorelin has the same ten-amino-acid sequence as the natural hypothalamic hormone GnRH (also called LHRH). The native hormone is broken down within minutes, which is why most therapeutic GnRH-pathway drugs are modified analogues rather than gonadorelin itself.
In research it is the reference agonist for the GnRH receptor and a baseline for studying how pulsatile versus continuous receptor stimulation changes downstream signalling.
What the research literature studies
- GnRH receptor signalling and desensitisation in cell models
- Pulsatile versus continuous stimulation of the receptor
- Structure-activity work on GnRH analogues
Evidence rating: 3/5
Early human trials. Decades of human pharmacology data, mostly from diagnostic use. Availability as a medicine varies by country. See our methodology for how levels are assigned.
- The native sequence is cleared within minutes, so stability matters more than for most peptides.
- Regulatory classification differs by country, so check local rules before ordering.
Regulatory status
The regulatory status of gonadorelin varies between countries and is mostly limited to diagnostic use. Research-grade material is not a medicine and must not be used in people or animals.
Reviewed November 2026.
Gonadorelin at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare Gonadorelin
Gonadorelin FAQ
Is gonadorelin the same as GnRH?
Yes. Gonadorelin is the name for the synthetic copy of the natural hormone; analogues such as leuprolide differ from it by design.
Why is the native hormone short-lived?
Peptidases cleave it rapidly. Many analogues substitute residues to slow that breakdown.
Where can I buy Gonadorelin for research?
Nordapep does not currently list Gonadorelin. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is Gonadorelin approved?
The regulatory status of gonadorelin varies between countries and is mostly limited to diagnostic use. Research-grade material is not a medicine and must not be used in people or animals.
Key terms for Gonadorelin
Cite this page
peptide.wiki. (2026). Gonadorelin: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/gonadorelin