At a glance
- Class
- KISS1 receptor agonist
- Receptor targets
- KISS1R (GPR54)
- Length
- 10 amino acids (C-terminal amide)
- Molecular mass
- ≈ 1.30 kDa
- Origin
- Fragment of human kisspeptin, produced synthetically
- Research area
- Reproductive & neuroendocrine
- Also known as
- KP-10, Metastin (45-54)
What Kisspeptin-10 is
Kisspeptins are cut from a 145-residue precursor encoded by the KISS1 gene. Kisspeptin-54 is the main circulating form, and kisspeptin-10 is the shortest fragment that keeps full receptor activity.
Investigator-led studies, notably at Imperial College London, have used kisspeptin to map reproductive-hormone signalling in volunteers, and kisspeptin-54 has been tested as a trigger of egg maturation in IVF. Kisspeptin-10 has a half-life of only a few minutes, so it is mainly a physiology tool.
What the research literature studies
- KISS1R binding and signalling in cell-based assays
- Hypothalamic control of GnRH release in animal models
- Peptide stability: why the 10-residue fragment clears far faster than kisspeptin-54
Evidence rating: 3/5
Early human trials. Investigator-led human physiology studies. No approved product. See our methodology for how levels are assigned.
- Most human studies use kisspeptin-54, not kisspeptin-10.
- The short half-life limits what a single fragment can show.
Regulatory status
Kisspeptin is not an approved medicine with the MHRA, EMA or FDA. Research-grade material must not be used in people or animals.
Reviewed November 2026.
Kisspeptin-10 at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare Kisspeptin-10
Kisspeptin-10 FAQ
What is the difference between kisspeptin-10 and kisspeptin-54?
Kisspeptin-54 is the longer circulating form and kisspeptin-10 is its active C-terminal end. Kisspeptin-54 lasts longer in the body, which is why most clinical studies use it.
Where can I buy Kisspeptin-10 for research?
Nordapep does not currently list Kisspeptin-10. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is Kisspeptin-10 approved?
Kisspeptin is not an approved medicine with the MHRA, EMA or FDA. Research-grade material must not be used in people or animals.
Key terms for Kisspeptin-10
Further reading
Cite this page
peptide.wiki. (2026). Kisspeptin-10: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/kisspeptin-10