Glossary
Aggregation
The clumping together of peptide molecules into insoluble assemblies. It is why native human amylin cannot be used directly, and why analogues such as pramlintide were engineered.
Relevant compounds
Further reading
- Peptide solubility basics: how sequence decides what dissolves
Why some peptides dissolve in water and others need acid, base or organic solvent: net charge, hydrophobic residues and the logic of choosing a solvent.
- Incretin and amylin peptides explained: GLP-1, GIP, glucagon and amylin
A plain-English map of the receptors behind semaglutide, tirzepatide, retatrutide, cagrilintide and the earlier GLP-1 analogues, and how each added a target.
For laboratory research only. Nothing on peptide.wiki is medical advice. The compounds described are not for human or veterinary use, and research-grade material is not a medicine.