At a glance
- Class
- Neuropeptide (receptor undefined)
- Receptor targets
- Not defined
- Length
- 9 amino acids
- Molecular mass
- ≈ 849 Da
- Origin
- Isolated from rabbit blood, produced synthetically
- Research area
- Neuro & longevity research
- Also known as
- Delta sleep-inducing peptide
What DSIP is
Delta sleep-inducing peptide was reported by a Swiss group in 1977 after experiments with cerebral venous blood from sleeping rabbits. The sequence is Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu.
Replication has been difficult. Later work found DSIP-like immunoreactivity in many tissues, but no dedicated receptor has been identified, and the peptide is broken down quickly in plasma. It is regarded as a poorly characterised tool compound.
What the research literature studies
- Sleep-architecture endpoints in animal models
- Plasma stability and degradation by peptidases
- Cross-reactivity of DSIP antibodies with unrelated proteins
Evidence rating: 1/5
Limited, preclinical or single-group. Small human studies with mixed results. Mechanism not established. See our methodology for how levels are assigned.
- No receptor or precursor gene has been firmly identified.
- Early positive findings were not consistently replicated.
Regulatory status
DSIP is not an approved medicine with the MHRA, EMA or FDA. Research-grade material must not be used in people or animals.
Reviewed November 2026.
DSIP at Nordapep: sizes and price per mg
Every size, its price and the cost per milligram, so you can choose the best-value vial for your protocol.
Not currently listed at Nordapep.
Compare DSIP
DSIP FAQ
Is DSIP related to Epithalon?
No. They are unrelated sequences that are studied in neighbouring areas such as sleep and circadian-rhythm models.
Where can I buy DSIP for research?
Nordapep does not currently list DSIP. You can ask Nordapep about availability, or compare related compounds that are in stock.
Is DSIP approved?
DSIP is not an approved medicine with the MHRA, EMA or FDA. Research-grade material must not be used in people or animals.
Cite this page
peptide.wiki. (2026). DSIP: research peptide profile. peptide.wiki. https://www.peptide.wiki/peptides/dsip